You cannot modify the End Point URL resource path configured on a Connect REST after you finalize and lock the rule. To be able to maintain different end point system URLs and reference them dynamically, the Healthcare API configuration provide a pre-configured node level dynamic settings data page called D_HCSettings. For all the connect rules referred in this document, the Resource path points to this page as referenced parameter to retrieve the EndPointURL for the given resource.
The data source configured to fetch the end point URL is a Data Transform rule called LoadHCSettings. The rule is configured with URLs for a test reference system used internally for testing the Healthcare APIs. The rule is marked for Extension and is expected to be updated in your application with URLs for your own source systems for the different resources.